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ACS Prostate Screening Guidelines

March 6th, 2010

The American Cancer Society’s (ACS) latest pronouncement on prostate cancer screening has them pulling back from their past recommendations.  They are no longer recommending yearly PSA and digital rectal examinations (DRE) but instead stressing that the patient should make an informed consent in consultation with his physician. 

ACS guideline:
Beginning at age 50, asymptomatic average-risk men with at least a 10-year life expectancy should receive information that allows them to make an informed decision, in collaboration with their healthcare providers, about prostate cancer screening

Despite the clear fact that PSA is the most accurate single cancer detection test in oncology, recent complaints about false positive test results (as occurs with all tests) and an inability to differentiate the most dangerous prostate cancers has the ACS backtracking on its prior pronouncements.  The America Urological Association (AUA) and the ACS are no longer in agreement about who should be screened.  This is a complex issue that even the experts do not agree, making it even more puzzling that the ACS is abdicating its leadership role and now wants to leave this controversy up to the patient. Read more…

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New Prostate Cancer Vaccine Promising

July 16th, 2009

The American Society of Clinical Oncology recently reported favorable results of a Phase 2 therapeutic trial of a vaccine called Prostvac-VF in the treatment of men with metastatic hormone-refractory prostate cancer.  Men who received the vaccine had a median overall survival that was 8.5 months longer than the placebo group.  Note that this data will need to be verified in Phase 3 trials.

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Wine and cancer risk

February 19th, 2009

A study from the National Cancer Institute in Paris reports that as little as a half glass of wine per day increases the risk of colon cancer by nine percent and the risk of mouth cancer by 168 percent.  This study confirms other studies that found alcohol increases the risk of some cancers.  Drinking alcohol and smoking increases the risk even further they report.  (Dr. Mac notes - It doesn’t seem anything is safe these days.)

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